Clinical Study on Ozone Haridradya taila

Clinical Study to assess the tolerability and effectiveness of Haridradya Taila in Acne and Acne-induced Post-inflammatory Hyperpigmentation

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Abstract

Introduction:
Acne is a condition of the pilosebaceous glands of skin characterized by anomalies in the production of sebum which includes both non-inflammatory lesions such as comedones (open and closed) and inflammatory lesions like pustules, papules and nodules. Patients with acne frequently seek treatment in inflammatory lesions state. Haridradya Taila is a classical preparation mentioned in kshudra rogadhikar of Chakradatta. The present study aimed to evaluate the safety and efficacy of haridradya taila in acne and acne induced post inflammatory hyperpigmentation. Total fifty patients in the age group of 18-45 years having mild to moderate acne and acne induced post inflammatory hyperpigmentation were enrolled. The statistical significance of the data was examined using SPSS. Clinical trial results were statistically significant for acne and acne induced post inflammatory hyperpigmentation. The results of this study suggest Haridradya Taila is safe and effective in the treatment of mild to moderate acne and acne induced post inflammatory hyperpigmentation.

Efficacy of Ozone Haridradya taila

1. More than 77% reduction in inflammatory lesion count and more than 74% reduction was observed in non inflammatory lesion count in 8 week study.

2. 23 patients had (80-100 %) complete relief, 11 patients show moderate (60-80 %) relief, 8 patients show mild (40-60%) relief in inflammatory lesions.

3. Haridradya taila has soothing effect on all patients and Erythema, Edema, Dryness and Peeling was reduced in 85.96%, 72%, 83.53%, 75.86% patients respectively.

Visible results after treatment

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Visible results after treatment

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Visible results after treatment

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Conclusion

Haridradya taila shows significant results in reducing Overall Disease Severity, Pigmentary Intensity of hyperpigmented lesions, Area of hyperpigmented lesions (% Facial Area) and Degree of hypopigmentation. There was significant reduction in Erythema, Burning, Peeling, and Dryness. Local application of Haridradya Taila is safe and effective in management of mild to moderate acne.